It’s era to move towards nature for getting beneficial effects of plants having Antioxidant activity to fight against deleterious diseases.

Shivani Sharma¹, Manpreet Rana², Hitesh Kumar ³, Bharat Parashar^4.

¹Research scholar, Department of Pharmacy, Manav Bharti University, Solan (H.P).

²Research scholar, Department of Pharmacy, Manav Bharti University, Solan (H.P).

³Assistant professor, Department of Pharmacy, Manav Bharti University, Solan (H.P).

⁴HOD and Associate Professor, Department of Pharmacy, Manav Bharti University, Solan (H.P).

*Corresponding author Email:

ABSTRACT:

Medicinal system of drugs is shifting towards herbal drugs so it’s time to come close to nature. Now a day’s diseases are spreading worldwide in various individuals due to various reasons it may be due to eating hobbits, stress, lifestyle or some other factors like geographical area also plays a great role in it. So we have to implement more and more natural products in our diet to get rid of diseases. Cancer, atherosclerosis, stroke, diabetes, Alzheimer’s diseases are becoming common in our life. Antioxidants play a great role and are beneficial in our day to day life. Antioxidants acts as the body's first line of defense against damage from natural process called oxidation. Antioxidants have the property that they can protect from cancer. Plants are the main source of natural antioxidants, including several edible species. Among antioxidant molecules, tocopherols, carotenoids, ascorbic acids, and phenolic compounds stand out. Additionally, the antioxidants present in fruits and vegetables have been found to exhibit anticarcinogenic and antimutagenic. So, it’s the need of time to add more and more natural products in our diet for our better living style and to fight against various diseases with our natural products. And to cure various ailments with our own natural ways by adding natural products in our diet for our healthy living and prosperous living.

KEYWORDS: Antioxidants, cancer, natural antioxidants, carotenoids, aloe vera.

INTRODUCTION:

Antioxidants acts as the body's first line of defence against damage from natural process called oxidation. They destroy substances called free radicals which occur naturally in our body and are also left behind by smog, cigarette smoke and the sun's radiation.

Free radicals damage cell tissues, membranes and other structures through the process of oxidation which is why substances that prevent this damage are called "anti-oxidants".

Natural antioxidants have awakened a great deal of interest because of their health effects and positive image as substances acting against degenerative diseases and certain cancers. Therefore, owing to consumer concerns about the safety of synthetic antioxidants, the promotion of natural antioxidants has been greater than ever [Balsano et al , 2009]. Plants are the main source of natural antioxidants, including several edible species. Among antioxidant molecules, tocopherols, carotenoids, ascorbic acids, and phenolic compounds stand out. Additionally, the antioxidants present in fruits and vegetables have been found to exhibit anticarcinogenic and antimutagenic [Sun et al , 2002].

The natural food antioxidants have anticancer properties or they protected against cancer. Some of the examples of antioxidants are being given below.

1. Lycopene - red colour of tomotoes.

2. Beta carotene - the pigment in carrots

3. Resveratrol - red wine pigment

4. Flavonoids - tea leaves

5. Quercitin - red onions, apples

6. Proanthocyanidins - colouring matter of many fruits

7. Catechins stem bark - oak tree

Antioxidants are useful in lowering the incidence of cadiovascular diseases and are good anticancer agents. They also prevent aging such as atherosclerosis, coronary artery diseases. Antioxidants are beneficial for our better living and thus average human life span would be extended some more active years.Many Indian medicinal plants are considered potential sources of antioxidant compounds. In some cases, their active constituents are known. Antioxidant- based drug formulations are used for the prevention and treatment of complex diseases like atherosclerosis, stroke, diabetes, Alzheimer’s disease and cancer. (Devasagayam TPA et al , 2004).

ANTIOXIDANT PLANTS:

S. No	Name of Plant	Part of Plant	Active Principle/ extract	Reference
1	Acacia catechu	Whole plant	Aqueous extract, acid resin, flavones, coumarins, catechu tannic acid, catechin, red tannin, quarcetin	[Naik et al, 2003]
2	Acacia Senegal	Bark and	Gum acacia	[Chang et al, 2001]
3	Aloe vera	Leaves	Aloesin, saponin, glucosamines	[Khaing,2011]
4	Anadenanthra perigrina	heart wood	Tryptamines	[Almas et al, 2001]
5	Aspergillus fumigates	_	Flavonoids, phenolic acid	[Arora Singh et al 2011]
6	Avena sativa	Cereal	Water and 80% methanolic extract	[Sperling et al, 2002]
7	Butea monosperma	Bark	Flavonoids, terpenoids	[T.B DIVYA et al, 2011]
8	Coptis spp.	Root	Berberine, palmatine	[Song et al, 1992; Wang et al, 2001; Wang et al, 2000]
9	Datura metal	Leaf, bark	Saponin,flavonoids,tannin,phenol,alkaloids,glycerol,sterol,terpenoids	[Akharaiyi et al, 2011]
10	Dioscorea spp.	Rhizomes	Diosgenin, dioscorin, Spirostanol, saponin	[Agaghinikhan et al, 2000; Hou et al, 2001; Liu et al ,2002; Dong et al , 2001]
11	Dioscorea villosa	Tubers	Flavonoids, phenolic acid, tannins	[Roy et al, 2011]
12	Eleutherococcus senticosus	_	Eleutheroside	[Davydov et al, 2000]
13	Emblica officinalis	Fruit	Tannins, gallic acid, phyllemblin. Vitamin c	[Bhattacharya et al, 1999]
14	Eupatorium odoratum linn	Leaves	phenols	[Chakraborty et al, 2010]
15	Fogophyrum esculentum	Seeds	Rutin	[Park et al, 1997; Quetties et al, 2000]
16	Gaultheria procumbens	_	Aesculetin	[Duke et al, 1990]
17	Glycyrshiza glabra	Whole plant	Aqueous extract, Glycyrshizin, asparagin	[Naik et al, 2003]
18	Hydrastic Canadensis	_	Hydrastine, canadaline, berberine, canadine, hydrastine	[Seazzocchio et al, 2001; Gentry et al, 1998; Periesa et al, 2000; Lau et.al 2001]
19	Jatropha curcas	Latex, leaf	Flavonoids, phenolic, saponin, alkaloid	[Oskoueian et al, 2011]
20	Justica adhatoda	Leaves	Vasicine, ethanolic extract	[Singh et al, 2002]
21	Larrea divarticata	_	Nordihydroguaiaretic acid	[Anesini et al, 1999; Anesini et al, 1996; Quiroga et al, 2001; Mc Donald et al, 2001]
22	Melissa officinalis	_	Rosmarinic acid	[Larrondo et al, 1995; Lamaison et al 1991; Dimitrova et al, 1993]
23	Momordica charantia Linn	Whole plant	Aqueous extract, glucosides, albuminoids, chasantin	[Naik et al, 2003]
24	Mucuna pruriens	Seeds	Bufotenine, L-dopa alcohal extract	[Pras et al, 1993]
25	Paullinia cupana		Caffeine	[Mattei et al,1998]
26	Peumus boldus	Leaves	Boldine, benzylbenzoate	[Mattei et al, 1998]
27	Prunues domestics	Leaves	Methanolic extract, prunetin, genistein, quercetin	[Mattei et al, 1998]
28	Prosalea corylifolia	Seed, Leaves	Psoralen, bakuchicol, isopsoralin, corylin, bevachin, alcoholic extract	[Qamaruddin et al, 2001; Das et al, 1999;Zhang et al, 1995]
29	Punica granatum	Seed	Methanolic extract and tannin	[Musthy et al, 2002]
30	Spinacia oleraceal	Leaves	Folic acid	[Vasthi et al, 2011]
31	Soppura pachycarpa	_	Methanolic extract and tannin	[Yamahara et al, 1990; Park et al, 2003]
32	Tabebuia spp.	Bark	Lapachol, elemicin, transanetheol, aqueous and methanolic extract	[Pastillo et al, 2001; Laplaud et al, 1997]
33	Terminalia chebula	Bark	Tannin, gallic acid, chebulinic acid	[Naik et al, 2003]
34	Vaccinium myrtillus	_	Anthocynosides, flavonoides	[Colantuoni et al, 1991]

CONCLUSION:

Plants are the main source of natural antioxidants, including several edible species. Among antioxidant molecules, tocopherols, carotenoids, ascorbic acids, and phenolic compounds stand out. Antioxidant- based drug formulations are used for the prevention and treatment of complex diseases like atherosclerosis, stroke, diabetes, Alzheimer’s disease and cancer. The natural food antioxidants have anticancer properties or they protected against cancer. Some antioxidants present in our day to day life are Lycopene - red colour of tomotoes, Beta carotene - the pigment in carrots, Resveratrol - red wine pigment, Flavonoids - tea leaves, Quercitin - red onions, apples, Proanthocyanidins - colouring matter of many fruits, Catechins stem bark - oak tree. So various spices and food products are helpful for us to deal with various diseases and for our healthy, prosperous and disease free life of everyone.

ACKNOWLEDGEMENT:

The author would like to thank to parents, and respected teachers who helped them a lot to complete this article.

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Received on 18.04.2013 Accepted on 25.05.2013

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